THE RESPIRATORY METABOLISM OF MURINE LEPROSY BACILLI

The respiratory metabolism of murine leprosy bacilli.

Studies on the metabolism of murine leprosy bacilli. I. Stimulating effect of mitochondria extract of rat liver on the metabolism of bacilli.

Biochemical study on the metabolism of murine leprosy bacilli was first com menced by Hanks (1951). According to his report, the hydrogen transfer capacity of the bacilli was so feeble that only 0.8ƒÊmole of TTC (Triphenyl Tetrazolium Chloride) was reduced per mg nitrogen of the bacilli after 24 hours' incubation at 37•Ž. Soon after, Gray (1952) has found by manometric method that only 5 cmm of...

DIFFERENTIATION OF LEPROSY AND TUBERCLE BACILLI. 219 On the Differentiation of Leprosy and Tubercle Bacilli

Influence of physical and chemical factors on the hydrogen transfer capacity of murine leprosy bacilli.

Another paper (6) summarizes certain implications for leprosy research involved in successful application of metabolic methods to washed suspensions of M. leprae murium and by similar studies with cultivable mycobacteria. It must be emphasized that no attempt has been made previously to utilize metabolic methods in such manner that the data obtained could substitute for cultivation or infection...

-i the Infectiousness of Murine Leprosy Bacilli after Exposure to Different Conditions

Studies on murine leprosy bacilli were undertaken in this laboratory for the specific purpose of reinoculating animals with microorganisms which had been exposed to different experimental conditions. It was proposed in this way (a) to define those circumstances which are either favorable or unfavorable to survival and infectiousness of these microorganisms, and (b) to ascertain whether substanc...